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Willem F Wolkers Selected Research

Dehydration (Water Stress)

1/2021Drying and temperature induced conformational changes of nucleic acids and stallion sperm chromatin in trehalose preservation formulations.
10/2019Spectroscopic monitoring of transport processes during loading of ovarian tissue with cryoprotective solutions.
6/2016Mode of action of cryoprotectants for sperm preservation.
1/2015Use of in situ Fourier transform infrared spectroscopy to study freezing and drying of cells.
3/2013Osmotic stress and membrane phase changes during freezing of stallion sperm: mode of action of cryoprotective agents.
9/2012Freezing-induced cellular and membrane dehydration in the presence of cryoprotective agents.
5/2012Membrane phase behavior during cooling of stallion sperm and its correlation with freezability.
3/2011Membrane hydraulic permeability changes during cooling of mammalian cells.
8/2010Dehydrating phospholipid vesicles measured in real-time using ATR Fourier transform infrared spectroscopy.
8/2010Membrane permeability parameters for freezing of stallion sperm as determined by Fourier transform infrared spectroscopy.
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Willem F Wolkers Research Topics

Disease

13Dehydration (Water Stress)
01/2021 - 11/2005
3Hemolysis
03/2024 - 03/2012
3Neoplasms (Cancer)
12/2014 - 03/2007
1Wounds and Injuries (Trauma)
11/2023
1Thrombocytopenia (Thrombopenia)
10/2020
1Prostatic Neoplasms (Prostate Cancer)
10/2004

Drug/Important Bio-Agent (IBA)

5IceIBA
01/2015 - 03/2007
4Cryoprotective AgentsIBA
10/2019 - 03/2011
3Glycerol (Glycerine)FDA LinkGeneric
11/2023 - 08/2010
3TrehaloseIBA
11/2023 - 11/2005
3Phospholipids (Phosphatides)FDA LinkGeneric
09/2012 - 08/2010
2Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
03/2024 - 03/2011
2LipidsIBA
08/2010 - 05/2009
2Proteins (Proteins, Gene)FDA Link
03/2007 - 10/2004
1Hemoglobins (Hemoglobin)IBA
11/2023
1ChromatinIBA
01/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2021
1Deuterium Oxide (Heavy Water)IBA
10/2019
1Polysaccharides (Glycans)IBA
03/2013
1Protective AgentsIBA
05/2012
1Dimyristoylphosphatidylcholine (DMPC)IBA
03/2012
1Liposomes (Liposome)IBA
08/2010
1Phosphatidylcholines (Phosphatidylcholine)IBA
08/2010
1SolutionsIBA
05/2009
1Heat-Shock Proteins (Heat-Shock Protein)IBA
11/2005

Therapy/Procedure

1Platelet Transfusion (Blood Platelet Transfusions)
10/2020
1Therapeutics
12/2014
1Fluid Therapy (Oral Rehydration Therapy)
11/2005